News

October 2021

Cuyler spearheads a wonderful collaboration between the Sirota and Okimoto labs to generate a user friendly online interface that compares pediatric cancer cell lines and tumor samples through transcriptional profiling. Congratulations Cuyler! doi: https://doi.org/10.1101/2021.10.01.462682

Ji Won discovers how Capicua controls YAP1 through GGAA-type repeat elements. Congratulations Ji Won! Check out the preprint: https://papers.ssrn.com/sol3/cf_dev/AbsByAuth.cfm?per_id=4866056

June 2021

Rovika and Nick identify a new therapeutic vulnerability in CIC-DUX4 sarcomas. Check out their preprint: https://www.biorxiv.org/content/10.1101/2021.06.21.448439v1

The National Cancer Institute (R37 MERIT Award) and the Sarcoma Foundation of America graciously support our fight to end CIC-DUX4 sarcoma.

April 2021

Shigeki Nanjo receives a prestigous career development award from the Japanese Society for the Promotion of Science (KAKENHI)!

Our new collaboration with Rosanna Wustrack and Larry Fong focused on the host immune response to sarcomas is accepted for publication in Cancer Immunology, Immunotherapy. 

Children's Cancer Research Foundation (CCRF) is graciously supporting our fight to defeat CIC-DUX4 sarcoma. https://childrenscancer.org/ccrf-announces-10-5-million-in-new-grants-largest-amount-ever-awarded-in-one-year/

December 2020

Check out these two innovative collaborations that leverage our in vivo metastasis models! 

Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science 2021.  https://science.sciencemag.org/content/early/2021/01/21/science.abc1944

Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis. Oncogenesis 9, 102 2020. https://doi.org/10.1038/s41389-020-00286-8

August 2020

Ji Won Kim is the recipient of a prestigious Postdoctoral Fellowship from the National Research Foundation of Korea!

Congratulations to Ji Won and Rovika on their recently accepted Trends in Cancer review detailing the role of Capicua in Human Cancer.

 

July 2020

Nicholas Thomas joins the lab!

Our newest paper detailing a mechanism-based approach to degrade the CIC-DUX4 oncoprotein is accepted for publication in PNAS.

Proceedings of the National Academy of Sciences: 117 (34)

July 2019

Our paper focused on the molecular and functional characterization of the CIC-DUX4 fusion in sarcoma is published in JCI. 

June 2019

The Okimoto lab offically opens for business! Eric, Rovika, Ji Won, and Nehal join the team!

April 2019

Ross is the recipient of the Young Physician-Scientist Award from the American Society of Clinical Investigation.

https://www.the-asci.org/awards/ypsa/2019-recipients

July 2018

Ross receives an award from the UCSF Department of Medicine to establish a cohort of fusion-positive sarcomas.

https://medicine.ucsf.edu/news/brett-ley-and-ross-okimoto-received-dom-patient-cohort-grants

Ross helps to generate Tanzania's National Cancer Treatment Guidelines. 

https://globalcancer.ucsf.edu/news/ucsf-team-helps-shape-national-cancer-treatment-guidelines-tanzania

February 2018

Ross receives a K08 award from the National Cancer Institute.

January 2017

We identify capicua as a major regulator of metastasis.

https://www.ucsf.edu/news/2016/11/404986/mutant-protein-linked-spread-lung-cancer-within-body

Volume 49 Issue 1